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Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence

Aging is accompanied by a loss of muscle mass and function, termed sarcopenia, which causes numerous morbidities and economic burdens in human populations. Mechanisms implicated in age-related sarcopenia or frailty include inflammation, muscle stem cell depletion, mitochondrial dysfunction, and loss...

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Detalles Bibliográficos
Autores principales: Perez, Kevin, Ciotlos, Serban, McGirr, Julia, Limbad, Chandani, Doi, Ryosuke, Nederveen, Joshua P., Nilsson, Mats I., Winer, Daniel A., Evans, William, Tarnopolsky, Mark, Campisi, Judith, Melov, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792217/
https://www.ncbi.nlm.nih.gov/pubmed/36516485
http://dx.doi.org/10.18632/aging.204435