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Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence
Aging is accompanied by a loss of muscle mass and function, termed sarcopenia, which causes numerous morbidities and economic burdens in human populations. Mechanisms implicated in age-related sarcopenia or frailty include inflammation, muscle stem cell depletion, mitochondrial dysfunction, and loss...
Autores principales: | Perez, Kevin, Ciotlos, Serban, McGirr, Julia, Limbad, Chandani, Doi, Ryosuke, Nederveen, Joshua P., Nilsson, Mats I., Winer, Daniel A., Evans, William, Tarnopolsky, Mark, Campisi, Judith, Melov, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792217/ https://www.ncbi.nlm.nih.gov/pubmed/36516485 http://dx.doi.org/10.18632/aging.204435 |
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