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Research Progress of Population Pharmacokinetic of Metformin

Metformin is commonly used as first-line treatment for T2DM (type2 diabetes mellitus). Owing to the high pharmacokinetic (PK) variability, several population pharmacokinetic (PPK) models have been developed for metformin to explore potential covariates that affect its pharmacokinetic variation. This...

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Detalles Bibliográficos
Autores principales: Wang, Xiaohu, Tang, Jin, Shen, Chaozhuang, Wang, Xingwen, Hu, Hua, Xie, Haitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792241/
https://www.ncbi.nlm.nih.gov/pubmed/36578804
http://dx.doi.org/10.1155/2022/4071111