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SKAP2 Modular Organization Differently Recognizes SRC Kinases Depending on Their Activation Status and Localization
Dimerization of SRC kinase adaptor phosphoprotein 2 (SKAP2) induces an increase of binding for most SRC kinases suggesting a fine-tuning with transphosphorylation for kinase activation. This work addresses the molecular basis of SKAP2-mediated SRC kinase regulation through the lens of their interact...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792355/ https://www.ncbi.nlm.nih.gov/pubmed/36423812 http://dx.doi.org/10.1016/j.mcpro.2022.100451 |