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SKAP2 Modular Organization Differently Recognizes SRC Kinases Depending on Their Activation Status and Localization

Dimerization of SRC kinase adaptor phosphoprotein 2 (SKAP2) induces an increase of binding for most SRC kinases suggesting a fine-tuning with transphosphorylation for kinase activation. This work addresses the molecular basis of SKAP2-mediated SRC kinase regulation through the lens of their interact...

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Detalles Bibliográficos
Autores principales:	Levillayer, Laurine, Cassonnet, Patricia, Declercq, Marion, Santos, Mélanie Dos, Lebreton, Louis, Danezi, Katerina, Demeret, Caroline, Sakuntabhai, Anavaj, Jacob, Yves, Bureau, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792355/ https://www.ncbi.nlm.nih.gov/pubmed/36423812 http://dx.doi.org/10.1016/j.mcpro.2022.100451

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