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Xanthatin suppresses proliferation and tumorigenicity of glioma cells through autophagy inhibition via activation of the PI3K‐Akt–mTOR pathway

Glioma is the most common and aggressive primary brain tumor in adults with high morbidity and mortality. Rapid proliferation and diffuse migration are the main obstacles to successful glioma treatment. Xanthatin, a sesquiterpene lactone purified from Xanthium strumarium L., possesses a significant...

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Detalles Bibliográficos
Autores principales: Chen, Huaqing, Zhu, Tong, Huang, Xiaojie, Xu, Wenshuang, Di, Zemin, Ma, Yuyang, Xue, Min, Bi, Sixing, Shen, Yujun, Yu, Yongqiang, Shen, Yuxian, Feng, Lijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792428/
https://www.ncbi.nlm.nih.gov/pubmed/36572650
http://dx.doi.org/10.1002/prp2.1041