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Xanthatin suppresses proliferation and tumorigenicity of glioma cells through autophagy inhibition via activation of the PI3K‐Akt–mTOR pathway
Glioma is the most common and aggressive primary brain tumor in adults with high morbidity and mortality. Rapid proliferation and diffuse migration are the main obstacles to successful glioma treatment. Xanthatin, a sesquiterpene lactone purified from Xanthium strumarium L., possesses a significant...
Autores principales: | Chen, Huaqing, Zhu, Tong, Huang, Xiaojie, Xu, Wenshuang, Di, Zemin, Ma, Yuyang, Xue, Min, Bi, Sixing, Shen, Yujun, Yu, Yongqiang, Shen, Yuxian, Feng, Lijie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792428/ https://www.ncbi.nlm.nih.gov/pubmed/36572650 http://dx.doi.org/10.1002/prp2.1041 |
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