Effect of bacterial DNA enrichment on detection and quantification of bacteria in an infected tissue model by metagenomic next-generation sequencing

Before implementing metagenomic next-generation sequencing (mNGS) in the routine diagnostic laboratory, several challenges need to be resolved. To address strengths and limitations of mNGS in bacterial detection and quantification in samples with overwhelming host DNA abundance, we used the pig musc...

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Detalles Bibliográficos
Autores principales: Lazarevic, Vladimir, Gaïa, Nadia, Girard, Myriam, Mauffrey, Florian, Ruppé, Etienne, Schrenzel, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792467/
https://www.ncbi.nlm.nih.gov/pubmed/37938717
http://dx.doi.org/10.1038/s43705-022-00208-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792467/
https://www.ncbi.nlm.nih.gov/pubmed/37938717
http://dx.doi.org/10.1038/s43705-022-00208-2

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