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Effect of bacterial DNA enrichment on detection and quantification of bacteria in an infected tissue model by metagenomic next-generation sequencing
Before implementing metagenomic next-generation sequencing (mNGS) in the routine diagnostic laboratory, several challenges need to be resolved. To address strengths and limitations of mNGS in bacterial detection and quantification in samples with overwhelming host DNA abundance, we used the pig musc...
Autores principales: | Lazarevic, Vladimir, Gaïa, Nadia, Girard, Myriam, Mauffrey, Florian, Ruppé, Etienne, Schrenzel, Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792467/ https://www.ncbi.nlm.nih.gov/pubmed/37938717 http://dx.doi.org/10.1038/s43705-022-00208-2 |
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