Case report: TP53 and RB1 loss may facilitate the transformation from lung adenocarcinoma to small cell lung cancer by expressing neuroendocrine markers

INTRODUCTION: Transformation from lung adenocarcinoma (LUAD) to small cell lung cancer (SCLC) is one of the mechanisms responsible for acquired EGFR-TKIs resistance. Although it rarely happens this event determines a rapid disease deterioration and needs specific treatment. PATIENT AND METHOD: We re...

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Detalles Bibliográficos
Autores principales: Li, Jun, Wei, Bing, Feng, Junnan, Wu, Xinxin, Chang, Yuxi, Wang, Yi, Yang, Xiuli, Zhang, Haiyan, Han, Sile, Zhang, Cuiyun, Zheng, Jiawen, Groen, Harry J. M., van den Berg, Anke, Ma, Jie, Li, Hongle, Guo, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792468/
https://www.ncbi.nlm.nih.gov/pubmed/36583000
http://dx.doi.org/10.3389/fendo.2022.1006480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792468/
https://www.ncbi.nlm.nih.gov/pubmed/36583000
http://dx.doi.org/10.3389/fendo.2022.1006480

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