Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells

SARS-CoV viruses have been shown to downregulate cellular events that control antiviral defenses. They adopt several strategies to silence p53, key molecule for cell homeostasis and immune control, indicating that p53 has a central role in controlling their proliferation in the host. Specific action...

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Detalles Bibliográficos
Autores principales: Lodi, Giada, Gentili, Valentina, Casciano, Fabio, Romani, Arianna, Zauli, Giorgio, Secchiero, Paola, Zauli, Enrico, Simioni, Carolina, Beltrami, Silvia, Fernandez, Mercedes, Rizzo, Roberta, Voltan, Rebecca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792496/
https://www.ncbi.nlm.nih.gov/pubmed/36582523
http://dx.doi.org/10.3389/fphar.2022.1018761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792496/
https://www.ncbi.nlm.nih.gov/pubmed/36582523
http://dx.doi.org/10.3389/fphar.2022.1018761

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