GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation

BACKGROUND: The role of GLIS2 in fibrotic diseases is controversial. GLIS2 deficiency has been reported to contribute to renal fibrosis in mice and has also been reported to prevent high lipid-induced mice hepatic fibrosis. METHODS: Hepatic fibrosis in mice was induced by CCl4. Hematoxylin and eosin...

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Detalles Bibliográficos
Autores principales: Zhang, Haoye, Zhou, Pengcheng, Xing, Wu, Chen, Limin, Zhou, Yangmei, Yang, Hui, Fu, Kangkang, Liu, Zhenguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792572/
https://www.ncbi.nlm.nih.gov/pubmed/36397300
http://dx.doi.org/10.1016/j.jcmgh.2022.10.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792572/
https://www.ncbi.nlm.nih.gov/pubmed/36397300
http://dx.doi.org/10.1016/j.jcmgh.2022.10.015

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