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Viral delivery of a peptide-based immunomodulator enhances T cell priming during vaccination

Modern, subunit-based vaccines have so far failed to induce significant T cell responses, contributing to ineffective vaccination against many pathogens. Importantly, while today’s adjuvants are designed to trigger innate and non-specific immune responses, they fail to directly stimulate the adaptiv...

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Detalles Bibliográficos
Autores principales: Phares, Timothy W., Huang, Jing, Kotraiah, Vinayaka, Hauser, Mary J., Domi, Arban, Oruganti, Sreenivasa, Browne, Cecille D., Buontempo, Peter, Mansour, Marc, Pannucci, James, Tsuji, Moriya, Gutierrez, Gabriel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792674/
https://www.ncbi.nlm.nih.gov/pubmed/36582528
http://dx.doi.org/10.3389/fphar.2022.1029636