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Fatty acid composition and metabolic partitioning of α-linolenic acid are contingent on life stage in human CD3(+) T lymphocytes

INTRODUCTION: Immune function changes across the life course; the fetal immune system is characterised by tolerance while that of seniors is less able to respond effectively to antigens and is more pro-inflammatory than in younger adults. Lipids are involved centrally in immune function but there is...

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Detalles Bibliográficos
Autores principales: West, Annette L., von Gerichten, Johanna, Irvine, Nicola A., Miles, Elizabeth A., Lillycrop, Karen A., Calder, Philip C., Fielding, Barbara A., Burdge, Graham C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792684/
https://www.ncbi.nlm.nih.gov/pubmed/36582247
http://dx.doi.org/10.3389/fimmu.2022.1079642