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Metformin Ameliorates Epithelial–Mesenchymal Transition of Renal Tubular Epithelial Cells in Diabetes by Increasing Vitamin D Receptor Expression

BACKGROUND: Metformin is used as a first-line drug for the treatment of type 2 diabetes. Epithelial–mesenchymal transition (EMT) plays a significant role in the development of renal tubular damage in diabetic kidney disease. However, the underlying mechanisms of EMT in diabetic kidney disease are un...

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Detalles Bibliográficos
Autores principales: Wen, Wenjie, Huang, Bin, Ye, Shandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792813/
https://www.ncbi.nlm.nih.gov/pubmed/36582506
http://dx.doi.org/10.2147/DMSO.S389918