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Maintenance therapy of low-dose nivolumab, S-1, and leucovorin in metastatic pancreatic adenocarcinoma with a germline mutation of MSH6: A case report

Immune checkpoint inhibitors (ICIs) provide substantial benefits to a small subset of patients with advanced cancer with mismatch repair deficiency (MMRD) or microsatellite instability (MSI), including patients with pancreatic ductal adenocarcinoma (PDAC). However, the long duration of ICI treatment...

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Detalles Bibliográficos
Autores principales: Peng, Shang-Hsuan, Chen, Bang-Bin, Kuo, Ting-Chun, Lee, Jen-Chieh, Yang, Shih-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792834/
https://www.ncbi.nlm.nih.gov/pubmed/36582237
http://dx.doi.org/10.3389/fimmu.2022.1077840