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Developmental endothelial locus-1 attenuates palmitate-induced apoptosis in tenocytes through the AMPK/autophagy-mediated suppression of inflammation and endoplasmic reticulum stress

AIMS: Myokine developmental endothelial locus-1 (DEL-1) has been documented to alleviate inflammation and endoplasmic reticulum (ER) stress in various cell types. However, the effects of DEL-1 on inflammation, ER stress, and apoptosis in tenocytes remain unclear. METHODS: Human primary tenocytes wer...

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Detalles Bibliográficos
Autores principales: Park, Tae Jun, Park, Seung Yeon, Cho, Wonjun, Oh, Heeseung, Lee, Hyun Jung, Abd El-Aty, A. M., Bayram, Cemil, Jeong, Ji Hoon, Jung, Tae Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792873/
https://www.ncbi.nlm.nih.gov/pubmed/36458454
http://dx.doi.org/10.1302/2046-3758.1112.BJR-2022-0077.R2