Hydroxylation site–specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: Implications for SREBP-2 and LXR

The cholesterol metabolites, oxysterols, play central roles in cholesterol feedback control. They modulate the activity of two master transcription factors that control cholesterol homeostatic responses, sterol regulatory element–binding protein-2 (SREBP-2) and liver X receptor (LXR). Although the r...

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Detalles Bibliográficos
Autores principales: Saito, Hodaka, Tachiura, Wakana, Nishimura, Mizuki, Shimizu, Makoto, Sato, Ryuichiro, Yamauchi, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792893/
https://www.ncbi.nlm.nih.gov/pubmed/36423680
http://dx.doi.org/10.1016/j.jbc.2022.102733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792893/
https://www.ncbi.nlm.nih.gov/pubmed/36423680
http://dx.doi.org/10.1016/j.jbc.2022.102733

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