Cargando…

A novel intergenic enhancer that regulates Bdnf expression in developing cortical neurons

Brain-derived neurotrophic factor (BDNF) promotes neuronal differentiation and survival and is implicated in the pathogenesis of many neurological disorders. Here, we identified a novel intergenic enhancer located 170 kb from the Bdnf gene, which promotes the expression of Bdnf transcript variants d...

Descripción completa

Detalles Bibliográficos
Autores principales: Brookes, Emily, Martinez De La Cruz, Braulio, Boulasiki, Paraskevi, Au, Ho Yu Alan, Varsally, Wazeer, Barrington, Christopher, Hadjur, Suzana, Riccio, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792897/
https://www.ncbi.nlm.nih.gov/pubmed/36582820
http://dx.doi.org/10.1016/j.isci.2022.105695