Cargando…

NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet

Nudix hydrolase 7 (NUDT7) is an enzyme that hydrolyzes CoA species, is highly expressed in the liver, and resides in the peroxisomes. Peroxisomes are organelles where the preferential oxidation of dicarboxylic fatty acids occurs and where the hepatic synthesis of the primary bile acids cholic acid a...

Descripción completa

Detalles Bibliográficos
Autores principales: Vickers, Schuyler D., Shumar, Stephanie A., Saporito, Dominique C., Kunovac, Amina, Hathaway, Quincy A., Mintmier, Breeanna, King, Judy A., King, Rachel D., Rajendran, Vazhaikkurichi M., Infante, Aniello M., Hollander, John M., Leonardi, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792899/
https://www.ncbi.nlm.nih.gov/pubmed/36436558
http://dx.doi.org/10.1016/j.jbc.2022.102745