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NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet
Nudix hydrolase 7 (NUDT7) is an enzyme that hydrolyzes CoA species, is highly expressed in the liver, and resides in the peroxisomes. Peroxisomes are organelles where the preferential oxidation of dicarboxylic fatty acids occurs and where the hepatic synthesis of the primary bile acids cholic acid a...
Autores principales: | Vickers, Schuyler D., Shumar, Stephanie A., Saporito, Dominique C., Kunovac, Amina, Hathaway, Quincy A., Mintmier, Breeanna, King, Judy A., King, Rachel D., Rajendran, Vazhaikkurichi M., Infante, Aniello M., Hollander, John M., Leonardi, Roberta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792899/ https://www.ncbi.nlm.nih.gov/pubmed/36436558 http://dx.doi.org/10.1016/j.jbc.2022.102745 |
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