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Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses

As SARS-CoV-2 Omicron and other variants of concern (VOCs) continue spreading worldwide, development of antibodies and vaccines to confer broad and protective activity is a global priority. Here, we report on the identification of a special group of nanobodies from immunized alpaca with potency agai...

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Detalles Bibliográficos
Autores principales: Li, Mingxi, Ren, Yifei, Aw, Zhen Qin, Chen, Bo, Yang, Ziqing, Lei, Yuqing, Cheng, Lin, Liang, Qingtai, Hong, Junxian, Yang, Yiling, Chen, Jing, Wong, Yi Hao, Wei, Jing, Shan, Sisi, Zhang, Senyan, Ge, Jiwan, Wang, Ruoke, Dong, Jay Zengjun, Chen, Yuxing, Shi, Xuanling, Zhang, Qi, Zhang, Zheng, Chu, Justin Jang Hann, Wang, Xinquan, Zhang, Linqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792944/
https://www.ncbi.nlm.nih.gov/pubmed/36575191
http://dx.doi.org/10.1038/s41467-022-35642-2