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RANKL neutralisation prevents osteoclast activation in a human in vitro ameloblastoma-bone model

Ameloblastoma is a benign, locally invasive epithelial odontogenic neoplasm of the jaw. Treatment of choice is jaw resection, often resulting in significant morbidity. The aim of this study was to recapitulate ameloblastoma in a completely humanised 3D disease model containing ameloblastoma cells, o...

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Detalles Bibliográficos
Autores principales: Pape, Judith, Bakkalci, Deniz, Hosni, Rawiya Al, Simpson, Benjamin S, Heikinheimo, Kristiina, Fedele, Stefano, Cheema, Umber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793035/
https://www.ncbi.nlm.nih.gov/pubmed/36582941
http://dx.doi.org/10.1177/20417314221140500