Negative cooperativity underlies dynamic assembly of the Par complex regulators Cdc42 and Par-3

The Par complex polarizes diverse animal cells through the concerted action of multiple regulators. Binding to the multi-PDZ domain containing protein Par-3 couples the complex to cortical flows that construct the Par membrane domain. Once localized properly, the complex is thought to transition fro...

Descripción completa

Detalles Bibliográficos
Autores principales: Vargas, Elizabeth, Prehoda, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793311/
https://www.ncbi.nlm.nih.gov/pubmed/36436559
http://dx.doi.org/10.1016/j.jbc.2022.102749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793311/
https://www.ncbi.nlm.nih.gov/pubmed/36436559
http://dx.doi.org/10.1016/j.jbc.2022.102749

Ejemplares similares