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Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality

Clustered protocadherin is a family of cell-surface recognition molecules implicated in neuronal connectivity that has a diverse isoform repertoire and homophilic binding specificity. Mice have 58 isoforms, encoded by Pcdhα, β, and γ gene clusters, and mutant mice lacking all isoforms died after bir...

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Detalles Bibliográficos
Autores principales: Kobayashi, Hiroaki, Takemoto, Kenji, Sanbo, Makoto, Hirabayashi, Masumi, Hirabayashi, Takahiro, Hirayama, Teruyoshi, Kiyonari, Hiroshi, Abe, Takaya, Yagi, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793319/
https://www.ncbi.nlm.nih.gov/pubmed/36582829
http://dx.doi.org/10.1016/j.isci.2022.105766