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Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality
Clustered protocadherin is a family of cell-surface recognition molecules implicated in neuronal connectivity that has a diverse isoform repertoire and homophilic binding specificity. Mice have 58 isoforms, encoded by Pcdhα, β, and γ gene clusters, and mutant mice lacking all isoforms died after bir...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793319/ https://www.ncbi.nlm.nih.gov/pubmed/36582829 http://dx.doi.org/10.1016/j.isci.2022.105766 |