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Development of an anti-CAR antibody response in SIV-infected rhesus macaques treated with CD4-MBL CAR/CXCR5 T cells

T cells expressing a simian immunodeficiency (SIV)-specific chimeric antigen receptor (CAR) and the follicular homing molecule, CXCR5, were infused into antiretroviral therapy (ART) suppressed, SIV-infected rhesus macaques to assess their ability to localize to the lymphoid follicle and control the...

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Detalles Bibliográficos
Autores principales: Davey, Brianna C., Pampusch, Mary S., Cartwright, Emily K., Abdelaal, Hadia M., Rakasz, Eva G., Rendahl, Aaron, Berger, Edward A., Skinner, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793449/
https://www.ncbi.nlm.nih.gov/pubmed/36582226
http://dx.doi.org/10.3389/fimmu.2022.1032537