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Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes

PURPOSE: The contribution of common genetic variants to pre-cancer progression is understudied due to long follow-up time, rarity of poor outcomes and lack of available germline DNA collection. Alternatively, DNA from diagnostic archival tissue is available, but its somatic nature, limited quantity...

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Detalles Bibliográficos
Autores principales: Nachmanson, Daniela, Pagadala, Meghana, Steward, Joseph, Cheung, Callie, Bruce, Lauryn Keeler, Lee, Nicole Q., O’Keefe, Thomas J., Lin, Grace Y., Hasteh, Farnaz, Morris, Gerald P., Carter, Hannah, Harismendy, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793518/
https://www.ncbi.nlm.nih.gov/pubmed/36575447
http://dx.doi.org/10.1186/s12967-022-03810-z