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NetAct: a computational platform to construct core transcription factor regulatory networks using gene activity

A major question in systems biology is how to identify the core gene regulatory circuit that governs the decision-making of a biological process. Here, we develop a computational platform, named NetAct, for constructing core transcription factor regulatory networks using both transcriptomics data an...

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Detalles Bibliográficos
Autores principales: Su, Kenong, Katebi, Ataur, Kohar, Vivek, Clauss, Benjamin, Gordin, Danya, Qin, Zhaohui S., Karuturi, R. Krishna M., Li, Sheng, Lu, Mingyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793520/
https://www.ncbi.nlm.nih.gov/pubmed/36575445
http://dx.doi.org/10.1186/s13059-022-02835-3