Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen–glucose deprivation conditions

BACKGROUND: Brain lactate concentrations are enhanced in response to cerebral ischemia and promote the formation of reactive astrocytes, which are major components of the neuroinflammatory response and functional recovery, following cerebral ischemia. NDRG2 is upregulated during reactive astrocyte f...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Jinying, Ji, Tong, Li, Guichen, Zhang, Haiying, Zheng, Yangyang, Li, Meiying, Ma, Jie, Li, Yulin, Chi, Guangfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793555/
https://www.ncbi.nlm.nih.gov/pubmed/36572898
http://dx.doi.org/10.1186/s12974-022-02678-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793555/
https://www.ncbi.nlm.nih.gov/pubmed/36572898
http://dx.doi.org/10.1186/s12974-022-02678-6

Ejemplares similares