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Circulating messenger RNA variants as a potential biomarker for surveillance of hepatocellular carcinoma

BACKGROUND AND RATIONALE: Liver derived messenger ribonucleic acid (mRNA) transcripts were reported to be elevated in the circulation of hepatocellular carcinoma (HCC) patients. We now report the detection of high-risk mRNA variants exclusively in the circulation of HCC patients. Numerous genomic al...

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Detalles Bibliográficos
Autores principales: Block, Timothy, Zezulinski, Daniel, Kaplan, David E., Lu, Jingqiao, Zanine, Samantha, Zhan, Tingting, Doria, Cataldo, Sayeed, Aejaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793749/
https://www.ncbi.nlm.nih.gov/pubmed/36582804
http://dx.doi.org/10.3389/fonc.2022.963641