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Simultaneous mapping of 3D structure and nascent RNAs argues against nuclear compartments that preclude transcription

Mammalian genomes are organized into three-dimensional DNA structures called A/B compartments that are associated with transcriptional activity/inactivity. However, whether these structures are simply correlated with gene expression or are permissive/impermissible to transcription has remained large...

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Detalles Bibliográficos
Autores principales: Goronzy, Isabel N., Quinodoz, Sofia A., Jachowicz, Joanna W., Ollikainen, Noah, Bhat, Prashant, Guttman, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793828/
https://www.ncbi.nlm.nih.gov/pubmed/36450242
http://dx.doi.org/10.1016/j.celrep.2022.111730