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Simultaneous mapping of 3D structure and nascent RNAs argues against nuclear compartments that preclude transcription
Mammalian genomes are organized into three-dimensional DNA structures called A/B compartments that are associated with transcriptional activity/inactivity. However, whether these structures are simply correlated with gene expression or are permissive/impermissible to transcription has remained large...
Autores principales: | Goronzy, Isabel N., Quinodoz, Sofia A., Jachowicz, Joanna W., Ollikainen, Noah, Bhat, Prashant, Guttman, Mitchell |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793828/ https://www.ncbi.nlm.nih.gov/pubmed/36450242 http://dx.doi.org/10.1016/j.celrep.2022.111730 |
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