A biophysical model of viral escape from polyclonal antibodies

A challenge in studying viral immune escape is determining how mutations combine to escape polyclonal antibodies, which can potentially target multiple distinct viral epitopes. Here we introduce a biophysical model of this process that partitions the total polyclonal antibody activity by epitope and...

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Detalles Bibliográficos
Autores principales: Yu, Timothy C, Thornton, Zorian T, Hannon, William W, DeWitt, William S, Radford, Caelan E, Matsen, Frederick A, Bloom, Jesse D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793855/
https://www.ncbi.nlm.nih.gov/pubmed/36582502
http://dx.doi.org/10.1093/ve/veac110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793855/
https://www.ncbi.nlm.nih.gov/pubmed/36582502
http://dx.doi.org/10.1093/ve/veac110

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