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Role of histone methyltransferase SETDB1 in regulation of tumourigenesis and immune response

Epigenetic alterations are implicated in tumour immune evasion and immune checkpoint blockade (ICB) resistance. SET domain bifurcated histone methyltransferase 1 (SETDB1) is a histone lysine methyltransferase that catalyses histone H3K9 di- and tri-methylation on euchromatin, and growing evidence in...

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Detalles Bibliográficos
Autores principales: Zhao, Zhipeng, Feng, Lu, Peng, Xuerun, Ma, Tingnan, Tong, Rongsheng, Zhong, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793902/
https://www.ncbi.nlm.nih.gov/pubmed/36582533
http://dx.doi.org/10.3389/fphar.2022.1073713