Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation

Coproporphyrin ferrochelatases (CpfCs) are enzymes catalyzing the penultimate step in the coproporphyrin‐dependent (CPD) heme biosynthesis pathway, which is mainly utilized by monoderm bacteria. Ferrochelatases insert ferrous iron into a porphyrin macrocycle and have been studied for many decades, n...

Descripción completa

Detalles Bibliográficos
Autores principales: Dali, Andrea, Gabler, Thomas, Sebastiani, Federico, Destinger, Alina, Furtmüller, Paul Georg, Pfanzagl, Vera, Becucci, Maurizio, Smulevich, Giulietta, Hofbauer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Full‐length Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794026/
https://www.ncbi.nlm.nih.gov/pubmed/36479958
http://dx.doi.org/10.1002/pro.4534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794026/
https://www.ncbi.nlm.nih.gov/pubmed/36479958
http://dx.doi.org/10.1002/pro.4534

Ejemplares similares