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Extended regimen of a levonorgestrel/ethinyl estradiol transdermal delivery system: Predicted serum hormone levels using a population pharmacokinetic model

OBJECTIVE: This study employed population pharmacokinetic (popPK) models to predict levonorgestrel (LNG) and ethinyl estradiol (EE) exposure after dosing with the transdermal contraceptive TWIRLA(®) (LNG/EE TDS) as a 12-week extended regimen in a healthy female population. METHODS: PopPK models were...

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Detalles Bibliográficos
Autores principales: Stanczyk, Frank Z., Archer, David F., Lohmer, Lauren R. L., Pirone, Jason, Previtera, Michelle, Korner, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794042/
https://www.ncbi.nlm.nih.gov/pubmed/36574387
http://dx.doi.org/10.1371/journal.pone.0279640