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Sonodynamic therapy suppresses matrix collagen degradation in vulnerable atherosclerotic plaque by modulating caspase 3 - PEDF/HIF-1α - MMP-2/MMP-9 signaling in macrophages

BACKGROUND: The rupture of vulnerable atherosclerotic plaque is the main cause of acute ischemic vascular events, and is characterized by pathological degradation of matrix collagen in the fibrous cap. In a previous study, we reported that 5-aminolevulinic acid-mediated sonodynamic therapy suppresse...

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Detalles Bibliográficos
Autores principales: Tian, Yanfeng, Sheng, Siqi, Gao, Weiwei, Yao, Jianting, Tian, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794047/
https://www.ncbi.nlm.nih.gov/pubmed/36574366
http://dx.doi.org/10.1371/journal.pone.0279191