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Anomalies in dye-terminator DNA sequencing caused by a natural G-quadruplex
A G-rich DNA sequence from yeast that can form a non-canonical G-quadruplex structure was cloned into a plasmid vector and subjected to Sanger sequencing using dye-labeled dideoxynucleotides. Two different effects were observed. In one, presence of the G4 sequence on the template strand led to incor...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794070/ https://www.ncbi.nlm.nih.gov/pubmed/36574393 http://dx.doi.org/10.1371/journal.pone.0279423 |