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Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils

Intraperitoneal administration of hydrogen (H(2))-containing saline inhibited neuronal cell death in ischemic stroke in a number of animal models, but it is unknown whether H(2) is absorbed from the abdominal cavity into the blood and reaches the brain. In this study, we investigated whether intrape...

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Detalles Bibliográficos
Autores principales: Hirano, Momoko, Sugai, Kazuhisa, Fujisawa, Masahiko, Kobayashi, Eiji, Katsumata, Yoshinori, Hakamata, Yoji, Sano, Motoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794077/
https://www.ncbi.nlm.nih.gov/pubmed/36574398
http://dx.doi.org/10.1371/journal.pone.0279410