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Pharmacokinetics of hydrogen administered intraperitoneally as hydrogen-rich saline and its effect on ischemic neuronal cell death in the brain in gerbils
Intraperitoneal administration of hydrogen (H(2))-containing saline inhibited neuronal cell death in ischemic stroke in a number of animal models, but it is unknown whether H(2) is absorbed from the abdominal cavity into the blood and reaches the brain. In this study, we investigated whether intrape...
Autores principales: | Hirano, Momoko, Sugai, Kazuhisa, Fujisawa, Masahiko, Kobayashi, Eiji, Katsumata, Yoshinori, Hakamata, Yoji, Sano, Motoaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794077/ https://www.ncbi.nlm.nih.gov/pubmed/36574398 http://dx.doi.org/10.1371/journal.pone.0279410 |
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