A photocaged orexin-B for spatiotemporally precise control of orexin signaling

Orexin neuropeptides carry out important neuromodulatory functions in the brain, yet tools to precisely control the activation of endogenous orexin signaling are lacking. Here, we developed a photocaged orexin-B (photo-OXB) through a C-terminal photocaging strategy. We show that photo-OXB is unable...

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Detalles Bibliográficos
Autores principales: Duffet, Loïc, Tatarskiy, Petr V., Harada, Masaya, Williams, Elyse T., Hartrampf, Nina, Patriarchi, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794195/
https://www.ncbi.nlm.nih.gov/pubmed/36481097
http://dx.doi.org/10.1016/j.chembiol.2022.11.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794195/
https://www.ncbi.nlm.nih.gov/pubmed/36481097
http://dx.doi.org/10.1016/j.chembiol.2022.11.007

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