Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection

The Lassa virus is endemic in parts of West Africa, and it causes hemorrhagic fever with high mortality. The development of a recombinant protein vaccine has been hampered by the instability of soluble Lassa virus glycoprotein complex (GPC) trimers, which disassemble into monomeric subunits after ex...

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Detalles Bibliográficos
Autores principales: Brouwer, Philip J.M., Antanasijevic, Aleksandar, Ronk, Adam J., Müller-Kräuter, Helena, Watanabe, Yasunori, Claireaux, Mathieu, Perrett, Hailee R., Bijl, Tom P.L., Grobben, Marloes, Umotoy, Jeffrey C., Schriek, Angela I., Burger, Judith A., Tejjani, Khadija, Lloyd, Nicole M., Steijaert, Thijs H., van Haaren, Marlies M., Sliepen, Kwinten, de Taeye, Steven W., van Gils, Marit J., Crispin, Max, Strecker, Thomas, Bukreyev, Alexander, Ward, Andrew B., Sanders, Rogier W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794196/
https://www.ncbi.nlm.nih.gov/pubmed/36400021
http://dx.doi.org/10.1016/j.chom.2022.10.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794196/
https://www.ncbi.nlm.nih.gov/pubmed/36400021
http://dx.doi.org/10.1016/j.chom.2022.10.018

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