Formulation of tizanidine hydrochloride–loaded provesicular system for improved oral delivery and therapeutic activity employing a 2(3) full factorial design

Tizanidine hydrochloride (TZN) is one of the most effective centrally acting skeletal muscle relaxants. The objective of this study is to prepare TZN-loaded proniosomes (TZN-PN) aiming at enhanced oral delivery and therapeutic activity. TZN-PN were prepared by coacervation phase separation method. T...

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Detalles Bibliográficos
Autores principales: Mohsen, Amira Mohamed, El-Hashemy, Hadeer Ahmed, Salama, Abeer, Darwish, Asmaa Badawy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794545/
https://www.ncbi.nlm.nih.gov/pubmed/35927549
http://dx.doi.org/10.1007/s13346-022-01217-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794545/
https://www.ncbi.nlm.nih.gov/pubmed/35927549
http://dx.doi.org/10.1007/s13346-022-01217-3

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