qInward variability-based in-silico proarrhythmic risk assessment of drugs using deep learning model

Many researchers have suggested evaluation methods and Torsades de Pointes (TdP) metrics to assess the proarrhythmic risk of a drug based on the in silico simulation, as part of the Comprehensive in-vitro Proarrhythmia Assay (CiPA) project. In the previous study, we validated the robustness of 12 in...

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Detalles Bibliográficos
Autores principales: Jeong, Da Un, Qashri Mahardika T, Nurul, Marcellinus, Aroli, Lim, Ki Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794579/
https://www.ncbi.nlm.nih.gov/pubmed/36589462
http://dx.doi.org/10.3389/fphys.2022.1080190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794579/
https://www.ncbi.nlm.nih.gov/pubmed/36589462
http://dx.doi.org/10.3389/fphys.2022.1080190

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