Physiologically based pharmacokinetic modelling and simulation to predict the plasma concentration profile of schaftoside after oral administration of total flavonoids of Desmodium styracifolium

Introduction: The total flavonoids of Desmodium styracifolium (TFDS) are the flavonoid extracts purified from Desmodii Styracifolii Herba. The capsule of TFDS was approved for the treatment of urolithiasis by NMPA in 2022. Schaftoside is the representative compound of TFDS that possesses antilithic...

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Detalles Bibliográficos
Autores principales: Li, Xue, Chen, Chao, Ding, Nan, Zhang, Tianjiao, Zheng, Peiyong, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794590/
https://www.ncbi.nlm.nih.gov/pubmed/36588682
http://dx.doi.org/10.3389/fphar.2022.1073535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794590/
https://www.ncbi.nlm.nih.gov/pubmed/36588682
http://dx.doi.org/10.3389/fphar.2022.1073535

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