A new model for fatty acid hydroxylase-associated neurodegeneration reveals mitochondrial and autophagy abnormalities

Fatty acid hydroxylase-associated neurodegeneration (FAHN) is a rare disease that exhibits brain modifications and motor dysfunctions in early childhood. The condition is caused by a homozygous or compound heterozygous mutation in fatty acid 2 hydroxylase (FA2H), whose encoded protein synthesizes 2-...

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Detalles Bibliográficos
Autores principales: Mandik, Frida, Kanana, Yuliia, Rody, Jost, Misera, Sophie, Wilken, Bernd, Laabs von Holt, Björn-Hergen, Klein, Christine, Vos, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794614/
https://www.ncbi.nlm.nih.gov/pubmed/36589738
http://dx.doi.org/10.3389/fcell.2022.1000553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794614/
https://www.ncbi.nlm.nih.gov/pubmed/36589738
http://dx.doi.org/10.3389/fcell.2022.1000553

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