Recent changes in the mutational dynamics of the SARS-CoV-2 main protease substantiate the danger of emerging resistance to antiviral drugs

INTRODUCTION: The current coronavirus pandemic is being combated worldwide by nontherapeutic measures and massive vaccination programs. Nevertheless, therapeutic options such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main-protease (M(pro)) inhibitors are essential due to the on...

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Detalles Bibliográficos
Autores principales: Parigger, Lena, Krassnigg, Andreas, Schopper, Tobias, Singh, Amit, Tappler, Katharina, Köchl, Katharina, Hetmann, Michael, Gruber, Karl, Steinkellner, Georg, Gruber, Christian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794616/
https://www.ncbi.nlm.nih.gov/pubmed/36590977
http://dx.doi.org/10.3389/fmed.2022.1061142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794616/
https://www.ncbi.nlm.nih.gov/pubmed/36590977
http://dx.doi.org/10.3389/fmed.2022.1061142

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