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Infertile human endometrial organoid apical protein secretions are dysregulated and impair trophoblast progenitor cell adhesion

INTRODUCTION: Embryo implantation failure leads to infertility. As an important approach to regulate implantation, endometrial epithelial cells produce and secrete factors apically into the uterine cavity in the receptive phase to prepare the initial blastocyst adhesion and implantation. Organoids w...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Barton, Siena, Cui, Jinwei, Santos, Leilani L., Yang, Guannan, Stern, Catharyn, Kieu, Violet, Teh, Wan Tinn, Ang, Catarina, Lucky, Tarana, Sgroi, Joseph, Ye, Louie, Dimitriadis, Evdokia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794621/
https://www.ncbi.nlm.nih.gov/pubmed/36589798
http://dx.doi.org/10.3389/fendo.2022.1067648