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Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators

Selective elimination of tumors has always been the mainstay of oncology research. The on-going research underlying the cellular apoptotic mechanisms reveal caspases activation, especially the key effector caspase-3, as a personalized tumor-selective therapeutic strategy. Our continued research prot...

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Detalles Bibliográficos
Autores principales: Ayoup, Mohammed Salah, Wahby, Yasmin, Abdel-Hamid, Hamida, Abu-Serie, Marwa M., Teleb, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794698/
https://www.ncbi.nlm.nih.gov/pubmed/36575196
http://dx.doi.org/10.1038/s41598-022-26469-4