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Structure optimization of new tumor-selective Passerini α-acyloxy carboxamides as Caspase-3/7 activators
Selective elimination of tumors has always been the mainstay of oncology research. The on-going research underlying the cellular apoptotic mechanisms reveal caspases activation, especially the key effector caspase-3, as a personalized tumor-selective therapeutic strategy. Our continued research prot...
Autores principales: | Ayoup, Mohammed Salah, Wahby, Yasmin, Abdel-Hamid, Hamida, Abu-Serie, Marwa M., Teleb, Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9794698/ https://www.ncbi.nlm.nih.gov/pubmed/36575196 http://dx.doi.org/10.1038/s41598-022-26469-4 |
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